AFP Specific Liver Tumor Vaccines Inhibit Hepatocellular Carcinoma Growth
نویسندگان
چکیده
منابع مشابه
Lentivirally engineered dendritic cells activate AFP-specific T cells which inhibit hepatocellular carcinoma growth in vitro and in vivo.
α-fetoprotein (AFP), a tumor-associated antigen for hepatocellular carcinoma (HCC), is an established biomarker for HCC. In this study, we created a lentivirus expressing the AFP antigen and investigated the anti-tumor activity of AFP-specific CD8+ T cells, with and without CD4+ T cells, which were activated by either AFP peptide-pulsed or Lenti-AFP-engineered Dendritic cells (DCs) in vitro and...
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ژورنال
عنوان ژورنال: Hans Journal of Surgery
سال: 2012
ISSN: 2168-5584,2168-5576
DOI: 10.12677/hjs.2012.13003